Gene: [06^/MEKK4] MAP/ERK kinase kinase 4 (similar to Mouse MEK kinase 4); MAP kinase kinase kinase 4; MAP three kinase 1;

COM

Using radiation hybrid and human-rodent hybrid mapping panels, the MEKK4 gene was localized to Chr 6 (Nagase-1996)."

FUN

The MTK1 kinase mediates stress-induced activation of the p38 and JNK pathways (Takekawa-1996)."

REF

COD,LOC "Nagase T &: DNA Res, 3, N5, 321-329, 1996
COD,EXP,FUN "Takekawa M &: EMBO J, 16, N16, 4973-4982, 1997

KEY

pep, sign

CLA

coding, basic

LOC

06

MIM

MIM: 602425

EZN

ENZYME: 2.7.1.?

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